KDM1A Back

lysine (K)-specific demethylase 1A

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NCBI Description of KDM1A

This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants.

Community Annotation of KDM1A Add / Edit KDM1A: Annotations

No community annotations yet for KDM1A.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KDM1A is highly significantly mutated in
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KDM1A is significantly mutated in
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KDM1A is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for KDM1A