KCNMB1 Back

potassium large conductance calcium-activated channel, subfamily M, beta member 1

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NCBI Description of KCNMB1

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the product of this gene, the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits.

Community Annotation of KCNMB1 Add / Edit KCNMB1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KCNMB1 is highly significantly mutated in
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KCNMB1 is significantly mutated in
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KCNMB1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for KCNMB1