KCNK3 Back

potassium channel, subfamily K, member 3

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NCBI Description of KCNK3
This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene.

Community Annotation of KCNK3 Add / Edit KCNK3: Annotations

No community annotations yet for KCNK3.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KCNK3 is highly significantly mutated in
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KCNK3 is significantly mutated in
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KCNK3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for KCNK3