KCNK2 Back

potassium channel, subfamily K, member 2

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of KCNK2

This gene encodes one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the cell to control resting membrane potential. The channel can be opened, however, by certain anesthetics, membrane stretching, intracellular acidosis, and heat. Three transcript variants encoding different isoforms have been found for this gene.

Community Annotation of KCNK2 Add / Edit KCNK2: Annotations

No community annotations yet for KCNK2.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KCNK2 is highly significantly mutated in
(none)
KCNK2 is significantly mutated in
(none)
KCNK2 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for KCNK2