KCNK18 Back

potassium channel, subfamily K, member 18

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NCBI Description of KCNK18

Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains and the encoded protein functions as an outward rectifying potassium channel. A mutation in this gene has been found to be associated with migraine with aura.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


KCNK18 is highly significantly mutated in
KCNK18 is significantly mutated in
KCNK18 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for KCNK18