KCNK16 Back

potassium channel, subfamily K, member 16

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NCBI Description of KCNK16

The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is expressed predominantly in the pancreas and is activated at alkaline pH. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Community Annotation of KCNK16 Add / Edit KCNK16: Annotations

No community annotations yet for KCNK16.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KCNK16 is highly significantly mutated in
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KCNK16 is significantly mutated in
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KCNK16 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for KCNK16