KCNK10 Back

potassium channel, subfamily K, member 10

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NCBI Description of KCNK10
The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Community Annotation of KCNK10 Add / Edit KCNK10: Annotations

No community annotations yet for KCNK10.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KCNK10 is highly significantly mutated in
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KCNK10 is significantly mutated in
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KCNK10 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for KCNK10