KCNJ2 Back

potassium inwardly-rectifying channel, subfamily J, member 2

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of KCNJ2

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features.

Community Annotation of KCNJ2 Add / Edit KCNJ2: Annotations

No community annotations yet for KCNJ2.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KCNJ2 is highly significantly mutated in
(none)
KCNJ2 is significantly mutated in
(none)
KCNJ2 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for KCNJ2