KAZALD1 Back

Kazal-type serine peptidase inhibitor domain 1

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NCBI Description of KAZALD1
This gene encodes a secreted member of the insulin growth factor-binding protein (IGFBP) superfamily. It contains an N-terminal insulin growth factor-binding domain, a central Kazal-type serine protease inhibitor and follistatin-like domain, and a C-terminal immunoglobulin-like domain. Studies of the mouse ortholog suggest that this gene product may have a function in bone development and bone regeneration.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KAZALD1 is highly significantly mutated in
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KAZALD1 is significantly mutated in
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KAZALD1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for KAZALD1