KATNA1 Back

katanin p60 (ATPase-containing) subunit A 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of KATNA1
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of the AAA family of ATPases. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Community Annotation of KATNA1 Add / Edit KATNA1: Annotations

No community annotations yet for KATNA1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KATNA1 is highly significantly mutated in
(none)
KATNA1 is significantly mutated in
(none)
KATNA1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for KATNA1