KAT5 Back

K(lysine) acetyltransferase 5

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NCBI Description of KAT5

The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.

Community Annotation of KAT5 Add / Edit KAT5: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


KAT5 is highly significantly mutated in
KAT5 is significantly mutated in
KAT5 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for KAT5