inositol 1,4,5-trisphosphate receptor interacting protein

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NCBI Description of ITPRIP

This gene encodes a membrane-associated protein that binds the inositol 1,4,5-trisphosphate receptor (ITPR). The encoded protein enhances the sensitivity of ITPR to intracellular calcium signaling. Alternative splicing results in multiple transcript variants.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


ITPRIP is highly significantly mutated in
ITPRIP is significantly mutated in
ITPRIP is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for ITPRIP