External References:
Wikipedia
GeneCards
HUGO
COSMIC
Google Scholar
NCBI Description of ITPR3 |
This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth. |
Community Annotation of ITPR3 Add / Edit ITPR3: Annotations
No community annotations yet for ITPR3.
|
Figure notes
• "Mouse over" a mutation to see details. |
|
Click on a tumor type to see its full list of significant genes.
Data details