ITGB3 Back

integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)

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NCBI Description of ITGB3
The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ITGB3 is highly significantly mutated in
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ITGB3 is significantly mutated in
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ITGB3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ITGB3