ITGA9 Back

integrin, alpha 9

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NCBI Description of ITGA9
This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers.

Community Annotation of ITGA9 Add / Edit ITGA9: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ITGA9 is highly significantly mutated in
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ITGA9 is significantly mutated in
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ITGA9 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ITGA9