NCBI Description of ITGA2
|This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.|
Community Annotation of ITGA2 Add / Edit ITGA2: Annotations
No community annotations yet for ITGA2.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.