ITGA11 Back

integrin, alpha 11

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of ITGA11
This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form. Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this gene, but their biological validity is not determined.

Community Annotation of ITGA11 Add / Edit ITGA11: Annotations

No community annotations yet for ITGA11.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ITGA11 is highly significantly mutated in
(none)
ITGA11 is significantly mutated in
(none)
ITGA11 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ITGA11