ISYNA1 Back

inositol-3-phosphate synthase 1

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NCBI Description of ISYNA1

This gene encodes an inositol-3-phosphate synthase enzyme. The encoded protein plays a critical role in the myo-inositol biosynthesis pathway by catalyzing the rate-limiting conversion of glucose 6-phosphate to myoinositol 1-phosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 4.

Community Annotation of ISYNA1 Add / Edit ISYNA1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ISYNA1 is highly significantly mutated in
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ISYNA1 is significantly mutated in
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ISYNA1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ISYNA1