IRX3 Back

iroquois homeobox 3

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NCBI Description of IRX3
IRX3 is a member of the Iroquois homeobox gene family (see IRX1; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998 [PubMed 9427753]). Members of this family appear to play multiple roles during pattern formation of vertebrate embryos (Lewis et al., 1999 [PubMed 10370142]).[supplied by OMIM, Aug 2009].

Community Annotation of IRX3 Add / Edit IRX3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

IRX3 is highly significantly mutated in
(none)
IRX3 is significantly mutated in
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IRX3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for IRX3