IRX1 Back

iroquois homeobox 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of IRX1
This gene encodes a member of the Iroquois homeobox protein family. Homeobox genes in this family are involved in pattern formation in the embryo. The gene product has been identified as a tumor suppressor in gastric (PMID: 21602894, 20440264) and head and neck cancers (PMID: 18559491). A pseudogene of this gene is located on chromosome 13.

Community Annotation of IRX1 Add / Edit IRX1: Annotations

No community annotations yet for IRX1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

IRX1 is highly significantly mutated in
(none)
IRX1 is significantly mutated in
(none)
IRX1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for IRX1