IRF7 Back

interferon regulatory factor 7

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NCBI Description of IRF7
IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established.

Community Annotation of IRF7 Add / Edit IRF7: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

IRF7 is highly significantly mutated in
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IRF7 is significantly mutated in
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IRF7 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for IRF7