IRAK2 Back

interleukin-1 receptor-associated kinase 2

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NCBI Description of IRAK2

IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB.

Community Annotation of IRAK2 Add / Edit IRAK2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


IRAK2 is highly significantly mutated in
IRAK2 is significantly mutated in
IRAK2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for IRAK2