IQ motif containing GTPase activating protein 2

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NCBI Description of IQGAP2

This gene encodes a member of the IQGAP family. The protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility.

Community Annotation of IQGAP2 Add / Edit IQGAP2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


IQGAP2 is highly significantly mutated in
IQGAP2 is significantly mutated in
IQGAP2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for IQGAP2