INTS8 Back

integrator complex subunit 8

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NCBI Description of INTS8

This gene encodes a subunit of the Integrator complex which is involved in the cleavage of small nuclear RNAs U1 and U2 within the nucleus. The encoded protein associates with RNA polymerase II and is recruited to the U1 and U2 small nuclear RNA genes. Alternative splicing results in multiple transcript variants.

Community Annotation of INTS8 Add / Edit INTS8: Annotations

No community annotations yet for INTS8.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


INTS8 is highly significantly mutated in
INTS8 is significantly mutated in
INTS8 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for INTS8