INS-IGF2 Back

INS-IGF2

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of INS-IGF2
This locus includes two alternatively spliced read-through transcript variants which align to the INS gene in the 5' region and to the IGF2 gene in the 3' region. One transcript is predicted to encode a protein which shares the N-terminus with the INS protein but has a distinct and longer C-terminus, whereas the other transcript is a candidate for nonsense-mediated decay (NMD). The transcripts are imprinted and are paternally expressed in the limb and eye.

Community Annotation of INS-IGF2 Add / Edit INS-IGF2: Annotations

No community annotations yet for INS-IGF2.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

INS-IGF2 is highly significantly mutated in
(none)
INS-IGF2 is significantly mutated in
(none)
INS-IGF2 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for INS-IGF2