INPP5K Back

inositol polyphosphate-5-phosphatase K

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NCBI Description of INPP5K
This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified.

Community Annotation of INPP5K Add / Edit INPP5K: Annotations

No community annotations yet for INPP5K.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

INPP5K is highly significantly mutated in
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INPP5K is significantly mutated in
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INPP5K is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for INPP5K