INPP5A Back

inositol polyphosphate-5-phosphatase, 40kDa

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of INPP5A
The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.

Community Annotation of INPP5A Add / Edit INPP5A: Annotations

No community annotations yet for INPP5A.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

INPP5A is highly significantly mutated in
(none)
INPP5A is significantly mutated in
(none)
INPP5A is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for INPP5A