INPP4B Back

inositol polyphosphate-4-phosphatase, type II, 105kDa

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NCBI Description of INPP4B
INPP4B encodes the inositol polyphosphate 4-phosphatase type II, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate. There is limited data to suggest that the human type II enzyme is subject to alternative splicing, as has been established for the type I enzyme.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

INPP4B is highly significantly mutated in
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INPP4B is significantly mutated in
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INPP4B is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for INPP4B