INPP1 Back

inositol polyphosphate-1-phosphatase

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NCBI Description of INPP1

This gene encodes the enzyme inositol polyphosphate-1-phosphatase, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 1 of the inositol ring from the polyphosphates inositol 1,4-bisphosphate and inositol 1,3,4-trisphophosphate.

Community Annotation of INPP1 Add / Edit INPP1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


INPP1 is highly significantly mutated in
INPP1 is significantly mutated in
INPP1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for INPP1