INMT Back

indolethylamine N-methyltransferase

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NCBI Description of INMT
N-methylation of endogenous and xenobiotic compounds is a major method by which they are degraded. This gene encodes an enzyme that N-methylates indoles such as tryptamine. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream FAM188B (family with sequence similarity 188, member B) gene.

Community Annotation of INMT Add / Edit INMT: Annotations

No community annotations yet for INMT.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

INMT is highly significantly mutated in
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INMT is significantly mutated in
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INMT is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for INMT