inhibin, beta C

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NCBI Description of INHBC

This gene encodes the beta C chain of inhibin, a member of the TGF-beta superfamily. This subunit forms heterodimers with beta A and beta B subunits. Inhibins and activins, also members of the TGF-beta superfamily, are hormones with opposing actions and are involved in hypothalamic, pituitary, and gonadal hormone secretion, as well as growth and differentiation of various cell types. Sequence Note: The sequence X82540.1 is a chimeric mRNA clone. Only the inhibin beta C chain region was propagated into this RefSeq record.

Community Annotation of INHBC Add / Edit INHBC: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


INHBC is highly significantly mutated in
INHBC is significantly mutated in
INHBC is near significance in

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Data details

Mutation list for INHBC