ILKAP Back

integrin-linked kinase-associated serine/threonine phosphatase 2C

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NCBI Description of ILKAP
The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway.

Community Annotation of ILKAP Add / Edit ILKAP: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ILKAP is highly significantly mutated in
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ILKAP is significantly mutated in
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ILKAP is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ILKAP