IL20 Back

interleukin 20

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NCBI Description of IL20
The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.

Community Annotation of IL20 Add / Edit IL20: Annotations

No community annotations yet for IL20.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

IL20 is highly significantly mutated in
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IL20 is significantly mutated in
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IL20 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for IL20