IL18 Back

interleukin 18 (interferon-gamma-inducing factor)

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NCBI Description of IL18

The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of IL18 Add / Edit IL18: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


IL18 is highly significantly mutated in
IL18 is significantly mutated in
IL18 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for IL18