IL17D Back

interleukin 17D

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NCBI Description of IL17D
The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent.

Community Annotation of IL17D Add / Edit IL17D: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

IL17D is highly significantly mutated in
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IL17D is significantly mutated in
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IL17D is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for IL17D