IL13RA2 Back

interleukin 13 receptor, alpha 2

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NCBI Description of IL13RA2
The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

IL13RA2 is highly significantly mutated in
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IL13RA2 is significantly mutated in
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IL13RA2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for IL13RA2