IL10RB Back

interleukin 10 receptor, beta

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NCBI Description of IL10RB
The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.

Community Annotation of IL10RB Add / Edit IL10RB: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

IL10RB is highly significantly mutated in
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IL10RB is significantly mutated in
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IL10RB is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for IL10RB