IK Back

IK cytokine, down-regulator of HLA II

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of IK

The protein encoded by this gene was identified by its RED repeat, a stretch of repeated arginine, glutamic acid and aspartic acid residues. The protein localizes to discrete dots within the nucleus, excluding the nucleolus. Its function is unknown. This gene maps to chromosome 5; however, a pseudogene may exist on chromosome 2.

Community Annotation of IK Add / Edit IK: Annotations

No community annotations yet for IK.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


IK is highly significantly mutated in
IK is significantly mutated in
IK is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for IK