IFRD1 Back

interferon-related developmental regulator 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of IFRD1

This gene is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. Mutations in this gene are associated with sensory/motor neuropathy with ataxia. This gene may also be involved in modulating the pathogenesis of cystic fibrosis lung disease. Alternate splicing results in multiple transcript variants.

Community Annotation of IFRD1 Add / Edit IFRD1: Annotations

No community annotations yet for IFRD1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

IFRD1 is highly significantly mutated in
(none)
IFRD1 is significantly mutated in
(none)
IFRD1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for IFRD1