IFNG Back

interferon, gamma

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NCBI Description of IFNG

This gene encodes a member of the type II interferon family. The protein encoded is a soluble cytokine with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. Mutations in this gene are associated with aplastic anemia.

Community Annotation of IFNG Add / Edit IFNG: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

IFNG is highly significantly mutated in
(none)
IFNG is significantly mutated in
(none)
IFNG is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for IFNG