IFNAR2 Back

interferon (alpha, beta and omega) receptor 2

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NCBI Description of IFNAR2

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene.

Community Annotation of IFNAR2 Add / Edit IFNAR2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

IFNAR2 is highly significantly mutated in
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IFNAR2 is significantly mutated in
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IFNAR2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for IFNAR2