interferon induced transmembrane protein 3 (1-8U)

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NCBI Description of IFITM3

The protein encoded by this gene is an interferon-induced membrane protein that helps confer immunity to influenza A H1N1 virus, West Nile virus, and dengue virus. Two transcript variants, only one of them protein-coding, have been found for this gene. Another variant encoding an N-terminally truncated isoform has been reported, but the full-length nature of this variant has not been determined.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


IFITM3 is highly significantly mutated in
IFITM3 is significantly mutated in
IFITM3 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for IFITM3