IFIT1 Back

interferon-induced protein with tetratricopeptide repeats 1

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NCBI Description of IFIT1
This gene encodes a protein containing tetratricopeptide repeats that was originally identified as induced upon treatment with interferon. The encoded protein may inhibit viral replication and translational initiation. This gene is located in a cluster on chromosome 10 with five other closely related genes. There is a pseudogene for this gene on chromosome 13. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

Community Annotation of IFIT1 Add / Edit IFIT1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

IFIT1 is highly significantly mutated in
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IFIT1 is significantly mutated in
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IFIT1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for IFIT1