IFI6 Back

interferon, alpha-inducible protein 6

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NCBI Description of IFI6
This gene was first identified as one of the many genes induced by interferon. The encoded protein may play a critical role in the regulation of apoptosis. A minisatellite that consists of 26 repeats of a 12 nucleotide repeating element resembling the mammalian splice donor consensus sequence begins near the end of the second exon. Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described.

Community Annotation of IFI6 Add / Edit IFI6: Annotations

No community annotations yet for IFI6.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

IFI6 is highly significantly mutated in
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IFI6 is significantly mutated in
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IFI6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for IFI6