IFI30 Back

interferon, gamma-inducible protein 30

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NCBI Description of IFI30
The protein encoded by this gene is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing.

Community Annotation of IFI30 Add / Edit IFI30: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

IFI30 is highly significantly mutated in
(none)
IFI30 is significantly mutated in
(none)
IFI30 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for IFI30