IFFO1 Back

intermediate filament family orphan 1

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NCBI Description of IFFO1
This gene is a member of the intermediate filament family. Intermediate filaments are proteins which are primordial components of the cytoskeleton and nuclear envelope. The proteins encoded by the members of this gene family are evolutionarily and structurally related but have limited sequence homology, with the exception of the central rod domain. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of IFFO1 Add / Edit IFFO1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

IFFO1 is highly significantly mutated in
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IFFO1 is significantly mutated in
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IFFO1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for IFFO1