IER3 Back

immediate early response 3

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NCBI Description of IER3

This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not generate a valid protein.

Community Annotation of IER3 Add / Edit IER3: Annotations

No community annotations yet for IER3.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


IER3 is highly significantly mutated in
IER3 is significantly mutated in
IER3 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for IER3