IDO2 Back

indoleamine 2,3-dioxygenase 2

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NCBI Description of IDO2
Along with the enzymes encoded by the INDO (MIM 147435) and TDO2 (MIM 191070) genes, the enzyme encoded by the INDOL1 gene metabolizes tryptophan in the kynurenine pathway (Ball et al., 2007 [PubMed 17499941]).[supplied by OMIM, Feb 2011]. Sequence Note: The RefSeq transcript 3' UTR was derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used were based on transcript alignments.

Community Annotation of IDO2 Add / Edit IDO2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

IDO2 is highly significantly mutated in
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IDO2 is significantly mutated in
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IDO2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for IDO2