ID4 Back

inhibitor of DNA binding 4, dominant negative helix-loop-helix protein

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NCBI Description of ID4

This gene encodes a member of the inhibitor of DNA binding (ID) protein family. These proteins are basic helix-loop-helix transcription factors which can act as tumor suppressors but lack DNA binding activity. Consequently, the activity of the encoded protein depends on the protein binding partner. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

Community Annotation of ID4 Add / Edit ID4: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


ID4 is highly significantly mutated in
ID4 is significantly mutated in
ID4 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for ID4