ICOS Back

inducible T-cell co-stimulator

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of ICOS
The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.

Community Annotation of ICOS Add / Edit ICOS: Annotations

No community annotations yet for ICOS.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ICOS is highly significantly mutated in
(none)
ICOS is significantly mutated in
(none)
ICOS is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ICOS